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Our West Orange office will be permanently closed starting 9/17/21. Please visit us at our Whippany location.

Corneal collagen cross-linking

Corneal Cross-Linking

Keratoconus and other forms of corneal ectasia affect the health and shape of the cornea and could cause permanent damage to your vision.

Corneal cross-linking (CXL) is a safe outpatient procedure that can strengthen the collagen in weak corneas and prevent vision loss.

Learn how Dr. Kenneth S. Miller helps Northern New Jersey patients with ectasia from his offices in West Orange and Whippany, NJ...

Corneal collagen cross-linking

What Is Corneal Cross-Linking?

Minimally Invasive Treatment for Corneal Issues

Cross-linking is a minimally invasive treatment for corneal ectasia, which is the bulging and distortion of the cornea's contour. It strengthens the cornea using a combination of riboflavin (vitamin B2) eye drops and ultraviolet light.

Strengthens a Weakened Cornea

When exposed to a special ultraviolet light, the riboflavin eye drops promote the development of new, stable collagen fiber cross-links within the cornea. Thanks to corneal collagen cross-linking, the effects of ectasia can be mitigated.

Opens Up Vision Correction Opportunities

Corneal collagen cross-linking may be the first step in a vision correction treatment plan. With the cornea strengthened, patients can potentially undergo surgeries such as LASIK or PRK, or wear gas permeable contact lenses.

Reasons to Undergo Corneal Cross-Linking

Cross-linking is recommended to treat the following corneal problems:


Keratoconus is a progressive eye disease in which the structure of the cornea is weakened. Over time, this can cause the normally round cornea to bulge outward into a cone shape. The conical bulge in the cornea causes poor vision and may necessitate a corneal transplant if left untreated. The exact causes of keratoconus are still not known, but common risk factors include heredity, chronic eye inflammation, and chronic rubbing of the eyes.

Post-LASIK/PRK Ectasia

A rare side effect of LASIK and PRK, this form of ectasia occurs when the cornea is too thin following refractive surgery. Intraocular pressure causes the cornea to bulge outward in a similar fashion to keratoconus. During these laser eye surgeries, changes are made to the surface and structure of the cornea which can potentially compromise its shape and stability. Post-surgical ectasia can cause distorted vision, eyestrain, and headaches.

An FDA-Approved Treatment


In 2016, the Food and Drug Administration (FDA) approved the use of KXL System corneal cross-linking to treat keratoconus as well as corneal ectasia following refractive surgery procedures such as LASIK and PRK.

If you suffer from keratoconus, you are not alone...

Keratoconus Symptoms

  • Glare/halos
  • Poor night vision
  • Light sensitivity
  • Eye irritation
  • Eye strain/fatigue
  • Sudden worsening of vision

If you experience any of the above symptoms, be sure to speak with your eye doctor. Early detection and treatment of keratoconus can prevent the need for a corneal transplant.

Is Corneal Cross-Linking Right for Me? Speak with an Experienced Ophthalmologist

If you suffer from keratoconus or thinning corneas after LASIK, Dr. Miller and his team can help. Thanks to minimally invasive cross-linking, we can improve the strength and shape of imperfect corneas, preventing vision loss and improving the overall health of your eyes.

To learn more about your treatment options, contact the Laser Vision Correction Center of New Jersey online. You can also schedule a consultation by phone.

Call Our Office in West Orange

(973) 325-3300

Laser Vision Correction Center of New Jersey
Come visit the Laser Vision Correction Center of New Jersey.

"I would highly recommend Dr. Miller and his staff" Advanced Eye Care in Northern NJ




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Dr. Miller and his team have shown nothing but care and concern for me. They all, especially Dr. Miller, have gone beyond the call of duty. Great team and a great, gifted doctor!

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Michelle Mohr


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Just recently visited the new office in Whippany for a checkup. The new space is very well laid out and the staff was very accommodating. I would highly recommend Dr. Miller and his staff for all your vision needs.

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Corneal Cross-Linking vs. Corneal Transplant


Patients with advanced keratoconus will require a corneal transplant because their corneas have become dangerously thin. In fact, keratoconus is the leading cause of corneal transplant surgery in America. When possible, cross-linking is the preferred treatment option because it is more conservative and prevents the progression of keratoconus.

A safe, simple, and minimally invasive solution to keratoconus and post-LASIK ectasia...

Before and after CXL Before and after CXL

The Corneal Cross-Linking Procedure

Corneal collagen cross-linking is an outpatient procedure, and typically takes about an hour to complete.
Corneal collagen cross-linking is an outpatient procedure, and typically takes about an hour to complete.

Numbing Eye Drops

At the start of the cross-linking procedure, numbing eye drops are administered as well as sedation if needed. This ensures patients experience no pain or anxiety during the treatment process.

Removing the Epithelium

The epithelium is the thin outermost layer of the corneal surface. The epithelium is removed during the cross-linking procedure, which allows the medication to penetrate deeper into the corneal tissue. The epithelium will grow back during the healing process.

Applying Riboflavin

The vitamin B2 eye drops are applied to the corneal surface. We take time to ensure that the riboflavin solution reaches deep into the corneal tissue and helps create strong collagen cross-links.

Exposure to UV Light

Focused beams of ultraviolet light are shined into the eyes. The UV light activates the vitamin B2 in the corneal tissue, promoting the growth of new collagen. The new collagen will make the thin, weak sections of the cornea much stronger.

Placing a Bandage

At the end of the cross-linking process, a bandage contact lens is placed on the treated eyes. Dr. Miller will let patients know how long to keep their bandage contact lens in place to ensure optimal healing.

Recovery and Results What to Expect after Corneal Cross-Linking

During your initial recovery, it's important to keep the bandage contact lens in place as directed. In the first week after treatment, corneal cross-linking patients should avoid:

  • Rubbing or touching their eyes
  • Getting water in the eyes
  • Strenuous physical activities
  • Using eye makeup or eye creams
  • Smoky or dusty environments
Common temporary side effects of cross-linking include:
  • Mild discomfort
  • Light sensitivity
  • The sensation of something in the eye
  • Dry eyes
  • Blurry vision

Most patients will be able to resume normal activities a week or two after the cross-linking procedure. While your vision will be blurry at the beginning, cross-linking patients should notice dramatic improvements in their vision after about three weeks.

Woman relaxing on couch

We're Here for You While You're Healing


If you experience any severe side effects or have urgent concerns after corneal cross-linking, feel free to contact us at any time. We will provide answers to your questions, and ensure any complications are addressed as soon as possible.

Five-Star Eye Care Patients Love the Laser Vision Correction Center of New Jersey


Melissa Mendoza


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Great experience. They check all aspects of my vision and make recommendations based on the tests they gave. All of my questions were answered and no pressure was given when I inquired about laser vision correction.

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Marianne Kehoe


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Most thorough eye exam I've ever had. Staff is cordial and helpful. Doctors spend time with you and are pleasant and professional. I've been to eye doctors so hurried that I couldn't pick them out of a line-up. Dr. Miller and staff were focused and competent and did a good job.

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Laser Vision Correction Center of New Jersey office

Laser Vision Correction Center of New Jersey

Dr. Kenneth S. Miller is a board-certified ophthalmologist with 40 years of experience serving the Northern New Jersey area. He is a member of several professional organizations, including:

  • American Academy of Ophthalmology
  • American Society of Cataract and Refractive Surgery

To schedule a consultation at our practice, contact us online or call us in Whippany, NJ, at (973) 325-3300.

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Whippany Location

16 South Jefferson Rd.
2nd Floor
Whippany, NJ 07981

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